Description:NebuSelect™ Recombinant Human CEACAM-5/CD66e, His-tag(Cat#NBL-241343) is expressed in HEK293 with His tag at the C-terminus; It contains Lys35-Ala685.

Species:Human

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 72.42 kDa. Due to glycosylation, the protein migrates to 100-140 kDa based on Bis-Tris PAGE result.

Target Name:CEACAM-5/CD66e

Target Information:Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) was identified as a metastatic driver. CEACAM5 overproduction enriched for an epithelial gene expression pattern and facilitated tumor outgrowth at metastatic sites. Tissues from patients with metastatic breast cancer confirmed elevated levels of CEACAM5 in lung metastases relative to breast tumors, and an inverse correlation between CEACAM5 and the mesenchymal marker vimentin was demonstrated.

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)