Description:NebuSelect™ Recombinant Human RNF43, His-tag(Cat#NBL-241325) is expressed in HEK293 with His tag at the C-terminus.It contains Gly24-Tyr197.

Species:Human

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 20.14 kDa. Due to glycosylation, the protein migrates to 28-38 kDa based on Bis-Tris PAGE result.

Target Name:RNF43

Target Information:RNF43 (E3 ubiquitin-protein ligase RNF43 or RING-type E3 ubiquitin transferase RNF43) functions as a tumor suppressor, by exerting a predominant negative feedback mechanism in the Wnt/β-catenin signaling pathway. RNF43 inhibits Wnt/beta-catenin signaling by ubiquitinating Frizzled receptor and targeting it to the lysosomal pathway for degradation.

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)