Description:NebuSelect™ Recombinant Human CLEC4M/CD299(Cat#NBL-241271) is expressed in HEK293 without tag.It contains Gln71-Glu399.

Species:Human

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 37.72 kDa. Due to glycosylation, the protein migrates to 38-50 kDa based on Bis-Tris PAGE result.

Target Name:CLEC4M/CD299

Target Information:CLEC4M, also known as DC-SIGNR, L-SIGN or CD209L, is a Ca2+-dependent C-type lectin. CLEC4M and its homologue DC-SIGN are encoded by the closely related lectin gene cluster on chromosome 19p13.3. higher expression of CLEC4M is associated with poor clinical prognosis in lung cancer patients and enhances the resistance of NSCLC cells to cisplatin. Inhibition of CLEC4M expression significantly increased cisplatin sensitivity, suggesting potential clinical significance for targeting CLEC4M in overcoming cisplatin resistance.

Amino Acid Sequence: Gln71-Glu399

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)