Description:NebuSelect™ Recombinant HRSV (B, strain 18537) Pre-fusion glycoprotein F0, His-tag(Cat#NBL-241236) is expressed in HEK293 with His tag at the C-terminus.

Species:HRSV(B,strain18537)

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 56.50 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.

Target Name:Pre-fusion glycoprotein F0SpeciesHRSV (B, strain 18537)

Target Information:Respiratory syncytial virus (RSV) is a highly contagious childhood pathogen of the respiratory tract and is divided into two antigenic subtypes, A and B, based on the reactivity of the F and G surface proteins to monoclonal antibodies. Surface protein F (fusion protein) is responsible for fusion of viral and host cell membranes, as well as syncytium formation between viral particles. Its sequence is highly conserved between strains. F protein exists in multiple conformational forms. In the prefusion state (PreF), the protein exists in a trimeric form and contains the major antigenic site Ø which serves as a primary target of neutralizing antibodies in the body.

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)