Description:NebuSelect™ Recombinant Biotinylated Human FcRn, Avi-His-tag(Cat#NBL-240910) is expressed in HEK293 with His tag and Avi tag at the C-Terminus.It contains Ala24-Ser297(FCGRT)&Ile21-Met119(B2M).

Species:Human

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 46.5 kDa. Due to glycosylation, the protein migrates to 48-55 kDa based on Bis-Tris PAGE result.

Target Name:FcRnSynonymsFcRn alpha chain; FCGRT; FCRN; FCGRT&B2M

Target Information:The neonatal Fc receptor (FCRN) is an approximately 45 kDa transmembrane glycoprotein with structural homology to MHC class I proteins. It is widely expressed in endothelial and epithelial cells and plays an important role in IgG homeostasis and antigen presentation by dendritic cells.FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51, and p14 , and forms an MHC class I-like heterodimer.

Amino Acid Sequence: Ala24-Ser297(FCGRT) & Ile21-Met119(B2M)

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)