Description:NebuSelect™ Recombinant Human/Mouse/Rat GDF-8(Cat#NBL-240905) is expressed in HEK293 without tag.It contains Asp267-Ser375.

Species:Human/Mouse/Rat

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 12.40 kDa. Due to glycosylation, the protein migrates to 13-15 kDa based on Bis-Tris PAGE result.

Target Name:GDF-8

Target Information:Growth/differentiation factor 8 (GDF8), or myostatin, negatively regulates muscle mass. GDF8 is held in a latent state through interactions with its N-terminal prodomain. GDF8, like numerous TGF-β family members, is a disulfidelinked dimer that is synthesized as a precursor protein which requires cleavage by a furin-like protease to yield an N-terminal prodomain and a C-terminal mature, signaling domain.

Amino Acid Sequence: Asp267-Ser375

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)