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收藏Description:NebuSelect™ Recombinant Cynomolgus CD3E&CD3D/CD3 epsilon&CD3 delta, hFc-tag(Cat#NBL-240890) is expressed in HEK293 with hFc tag at the C-Terminus.It contains Gln22-Asp117(CD3E)&Phe22-Ala105(CD3D).
Species:Cynomolgus
Expression System:HEK293
Molecular Weight: The protein has a predicted MW of 36.9 kDa (CD3E) and 35.4 kDa (CD3D). Due to glycosylation,the protein migrates to 58-62 kDa (CD3E) and 44-46 kDa (CD3D) based on Bis-Tris PAGE result.
Target Name:CD3E&CD3D/CD3 epsilon&CD3 deltaSynonymsCD3; CD3e; CD3E; CD3d; T3D; CD3D; CD3E&CD3D; CD3 delta&CD3 epsilon
Target Information:T-cell surface glycoprotein CD3 epsilon&CD3 delta chain, also known as CD3E & CD3D , are single-pass type I membrane proteins.When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain.
Amino Acid Sequence: Gln22-Asp117(CD3E) & Phe22-Ala105(CD3D)
Purity:>95%
Endotoxin:<1EU/ug(LAL Method)