Description:NebuSelect™ Recombinant Cynomolgus IL-31, His-tag(Cat#NBL-240858) is expressed in HEK293 with His tag at the N-Terminus.It contains Leu27-Thr163.

Species:Cynomolgus

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 16.5 kDa. Due to glycosylation, the protein migrates to 23-30 kDa based on Bis-Tris PAGE result.

Target Name:IL-31SynonymsInterleukin-31； IL-31；IL31

Target Information:Many autoimmune skin diseases, such as bullous pemphigoid (BP), psoriasis and certain types of chronic urticaria, are associated with intensive pruritus. While histamine and neuropeptides have previously been ascribed to play a role in itch that accompanies these diseases, recent evidence suggests that the pruritogenic cytokine interleukin (IL)-31 is a major driver of pruritic responses. IL-31 was originally shown to be produced by activated helper T cells, particularly Th2 cells, mast cells, macrophages and dendritic cells.

Amino Acid Sequence: Leu27-Thr163

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)