Description:NebuSelect™ Recombinant Human Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer, Avi-His-tag(Cat#NBL-240850) is expressed in HEK293 with His tag and Avi tag at the C-Terminus.It contains Phe31-Val992(ITGAV) acidic tail&GLy27-Asp718(ITGB3) basic tail.

Species:Human

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 114 kDa (ITGAV)&81.3 kDa (ITGB3). Due to glycosylation,the protein migrates to 85-140 kDa based on Bis-Tris PAGE result.

Target Name:Integrin alpha V beta 3 (ITGAV&ITGB3) HeterodimerSynonymsIntegrin alpha V beta 3; beta3; alphaV; ITGAV&ITGB3

Target Information:ITGAV&ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGAV&ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling. ITGAV&ITGB3 binds to FGF2 and this binding is essential for FGF2 signaling. ITGAV&ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling. ITGAV&ITGB3 binds to IGF2 and this binding is essential for IGF2 signaling.

Amino Acid Sequence: Phe31-Val992(ITGAV)acidic tail & Gly27-Asp718(ITGB3)basic tail

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)