Description:NebuSelect™ Recombinant Human Kremen-2, His-tag(Cat#NBL-240849) is expressed in HEK293 with His tag at the C-Terminus.It contains Gly26-Ala364.

Species:Human

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 37.1 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result.

Target Name:Kremen-2SynonymsKRM2; KREMEN2; Kremen-2; Dickkopf receptor 2

Target Information:Kremen2 (Krm2) plays an important role in embryonic development, bone formation, and tumorigenesis as a crucial regulator of classical Wnt/β-catenin signaling pathway. Compared to para-cancerous tissues, Krm2 was significantly up-regulated in gastric cancer tissues and was positively correlated with the pathological grade of gastric cancer patients. Krm2 can be a potent candidate for designing of targeted therapy.

Amino Acid Sequence: Gly26-Ala364

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)