Description:NebuSelect™ Recombinant Biotinylated Human TNFR2/CD120b/TNFRSF1B, His-tag(Cat#NBL-240813) is expressed in HEK293 with His tag at the C-Terminus.It contains Leu23-Asp257.

Species:Human

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 26.2 kDa. Due to glycosylation, the protein migrates to 40-60 kDa based on Bis-Tris PAGE result.

Target Name:TNFR2/CD120b/TNFRSF1B

Target Information:Tumor Necrosis Factor Receptor II (TNF RII), also known as TNFRSF1B, p75/p80, and CD120b, is a type I transmembrane protein that belongs to the TNF receptor superfamily. It has a molecular weight of approximately 75 kDa.Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.

Amino Acid Sequence: Leu23-Asp257

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)