Description:NebuSelect™ Recombinant Rat GARP&Latent TGF Beta 1 Complex, Avi-His-tag(Cat#NBL-240811) is expressed in HEK293 with His tag and Avi Tag at the C-Terminus.It contains Ile18-Asn628(GARP)&Leu30-Arg278(Latent TGF Beta 1).

Species:Rat

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 69.80 kDa (GARP)&41.28 kDa (Latent TGF beta 1). Due to glycosylation, the protein migrates to 70-80 kDa (GARP)&42-48 kDa&13 kDa (Latent TGF beta 1) based on Bis-Tris PAGE result.

Target Name:GARP&Latent TGF Beta 1 Complex

Target Information:GARP&Latent TGF Beta is a complex found on surface of many types of cells. In Tregs, GARP is involved in TCR-mediated activation of Latent TGF-β and thus promoting secretion and activation of TGF-β. Integrin αvβ8 on the surface of immune cells and other cells recognizes RGD in LAP, resulting in the release of mature TGF-β from the TGF-β&GARP complex.

Amino Acid Sequence: Ile18-Asn628(GARP) & Leu30-Arg278(Latent TGF Beta 1)

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)