Description:NebuSelect™ Recombinant Human Her2/ErbB2, Avi-His-tag(Cat#NBL-240735) is expressed in HEK293 with His tag and Avi tag at the C-Terminus.It contains Thr23-Thr652.

Species:Human

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 72.3 kDa. Due to glycosylation, the protein migrates to 80-100 kDa based on Bis-Tris PAGE result.

Target Name:Her2/ErbB2SynonymsCD340; EGFR2; ErbB2; HER2; HER-2; herstatin; MLN 19; MLN19; Neu Oncogene; NEUHER-2/neu; NGL; p185erbB2; TKR1; ERBB2; HER-2/neu; NEU; ENV; ENVW; ERVWE1; HERV-7q; HERV-W-ENV; HERV7Q; HERVW; HERVWENV

Target Information:ErbB2, also called Neu and Her2 (human epidermal growth factor receptor 2), is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors. ErbB family members serve as receptors for the epidermal growth factor (EGF) family of growth factors.Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane.

Amino Acid Sequence: Thr23-Thr652

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)