Description:NebuSelect™ Recombinant Human Activin A(Cat#NBL-240685) is expressed in HEK293 without tag.It contains Gly311-Ser426.

Species:Human

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 12.97 kDa. Due to glycosylation, the protein migrates to 14-15 kDa under reduced (R) condition, and 23-25 kDa under Non reducing (N) condition based on Bis-Tris PAGE result.

Target Name:Activin A

Target Information:Activin-A, a member of the TGF-β superfamily, Extensive research over the past decades illuminated fundamental roles for activin-A in essential biologic processes, including embryonic development, stem cell maintenance and differentiation, haematopoiesis, cell proliferation and tissue fibrosis. Activin-A signals through two type I and two type II receptors which, upon ligand binding, activate their kinase activity, phosphorylate the SMAD2 and 3 intracellular signaling mediators that form a complex with SMAD4, translocate to the nucleus and activate or silence gene expression.

Amino Acid Sequence: Gly311-Ser426

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)