Description:NebuSelect™ Recombinant Biotinylated Human Siglec-10, Avi-His-tag(Cat#NBL-240674) is expressed in HEK293 with His tag and Avi tag at the C-Terminus.It contains Met17-Thr546.

Species:Human

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 61.13 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Bis-Tris PAGE result.

Target Name:Siglec-10SynonymsSLG2; SIGLEC10; MGC126774; PRO940

Target Information:Siglec-10 is a ligand for CD52, the target of the therapeutic monoclonal antibody Alemtuzumab. It is also reported to bind to Vascular adhesion protein 1 (VAP-1) and to the co-stimulatory molecule CD24 also known as HSA (Heat-stable antigen).Siglecs (sialic acid binding Ig-like lectins) are I-type lectins that belong to the immunoglobulin superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by a varying number of Ig-like C2-type domains. Siglecs 5-11 constitute the CD33/Siglec-3 related group, and are differentially expressed in the hematopoietic system.

Amino Acid Sequence: Met17-Thr546

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)