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收藏Description:NebuSelect™ Recombinant Human CD3E&CD3D/CD3 epsilon&CD3 delta, hFc-tag(Cat#NBL-240670) is expressed in HEK293 with hFc at the C-Terminus.It contains Asp23-Asp126(CD3E)&Phe22-Ala105(CD3D).
Species:Human
Expression System:HEK293
Molecular Weight: The protein has a predicted MW of 37.8 kDa (CD3E) and 35.4 kDa (CD3D). Due to glycosylation, the protein migrates to 48-58 kDa (CD3E) and 42-48 kDa (CD3D) based on Bis-Tris PAGE result.
Target Name:CD3E&CD3D/CD3 epsilon&CD3 deltaSynonymsCD3; CD3e; CD3E; CD3d; T3D; CD3D; CD3E&CD3D; CD3 delta&CD3 epsilon
Target Information:T-cell surface glycoprotein CD3 epsilon & CD3 delta chain, also known as CD3E & CD3D , are single-pass type I membrane proteins.When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain.
Amino Acid Sequence: Asp23-Asp126(CD3E) & Phe22-Ala105(CD3D)
Purity:>95%
Endotoxin:<1EU/ug(LAL Method)