Description:NebuSelect™ Recombinant Human SEZ6, His-tag(Cat#NBL-240669) is expressed in HEK293 with His tag at the C-Terminus; It contains Leu20-His925.

Species:Human

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 98.9 kDa. Due to glycosylation, the protein migrates to 145-150 kDa based on Bis-Tris PAGE result.

Target Name:SEZ6SynonymsSEZ-6; SEZ6; BSRPC; BSRP-C

Target Information:Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform of Sez6 is cleaved by the β-amyloid precursor protein cleavage enzyme 1 (BACE1), resulting in Sez6 extracellular domain shedding from the neuron surface.

Amino Acid Sequence: Leu20-His925

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)