Description:NebuSelect™ Recombinant Human CHRDL1, His-tag(Cat#NBL-240654) is expressed in E.coli with His tag at the N-Terminus.It contains Glu28-Cys456.

Species:Human

Expression System:E.coli

Molecular Weight: The protein has a predicted MW of 50 kDa same as Bis-Tris PAGE result.

Target Name:CHRDL1SynonymsNeuralin-1; Neurogenesin-1; Ventroptin; CHRDL1; NRLN1; CHL; Chordin-like 1; CRDL1; dA141H5.1; VOPT

Target Information:CHRDL1 (Chordin-like 1) is a secreted protein that acts as an antagonist of bone morphogenetic protein (BMP). BMP plays a role as an activator of BMP receptor II (BMPR II), which mediates extracellular to intracellular signal transmission and is involved in carcinogenesis and metastasis.The hypermethylation of the CHRDL1 promoter in gastric cancer, which induced low expression of CHRDL1 and decreased its secretion to the supernatant.

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)