Description:NebuSelect™ Recombinant Mouse Hepcidin/HAMP, GST-tag(Cat#NBL-240640) is expressed in E.coli with GST tag at the N-Terminus.It contains Asp59-Thr83.

Species:Mouse

Expression System:E.coli

Molecular Weight: The protein has a predicted MW of 29.05 kDa same as Bis-Tris PAGE result.

Target Name:Hepcidin/HAMPSynonymsHamp1; Hepc; Hepc1; HFE2B; LEAP1; LEAP-1; PLTR

Target Information:Hepcidin, the main regulator of iron metabolism, is synthesized and released by hepatocytes in response to increased body iron concentration and inflammation. Deregulation of hepcidin expression is a common feature of genetic and acquired iron disorders: in Hereditary Hemochromatosis (HH) and iron-loading anemias low hepcidin causes iron overload, while in Iron Refractory Iron Deficiency Anemia (IRIDA) and anemia of inflammation (AI), high hepcidin levels induce iron-restricted erythropoiesis.

Amino Acid Sequence: Asp59-Thr83

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)