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收藏Description:NebuSelect™ Recombinant Cynomolgus PS20, His-tag(Cat#NBL-240606) is expressed in E.coli with His tag at the N-Terminus.It contains Lys32-Gln192.
Species:Cynomolgus
Expression System:E.coli
Molecular Weight: The protein has a predicted MW of 18.77 kDa. The protein migrates to 25-28 kDa based on Bis-Tris PAGE result.
Target Name:PS20
Target Information:The whey acidic protein family member, WFDC1/ps20 is a permissivity factor in HIV infection. Herein we describe a contrasting role for ps20 in limiting MHV-1 infection. Intranasal MHV-1 infection produces a respiratory infection in mice. Using ps20 knockout mice we provide evidence that intranasal MHV-1 infection results in increased lung viral titers in ps20(-/-) compared to ps20(/) mice. Roles for ps20 in regulating expression of neutrophil-specific chemotactic factors, thereby potentially modulating neutrophil migration, and in modulating neutrophil susceptibility to MHV-1 infection.
Amino Acid Sequence: Lys32-Gln192
Purity:>95%
Endotoxin:<1EU/ug(LAL Method)