Background
This gene encodes a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell-cell adhesion and play critical roles in cell differentiation and morphogenesis. The encoded protein is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis.
Dilutions
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Format
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human CDH6 (NP_004923.1).
Modification
Unmodified
Storage
-20°C
Images
Western blot analysis of extracts of various cell lines, using CDH6 antibody (144-08109) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 90s.

Immunohistochemistry of paraffin-embedded rat kidney using CDH6 antibody (144-08109) at dilution of 1:100 (40x lens).

Immunohistochemistry of paraffin-embedded human stomach using CDH6 antibody (144-08109) at dilution of 1:100 (40x lens).

Expiration:
12 months from the date of shipment when stored properly.