Background
This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is a component of three different protein complexes termed biogenesis of lysosome-related organelles complex (BLOC)-3, BLOC4, and BLOC5. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 1. Alternative splicing results in multiple transcript variants. A pseudogene related to this gene is located on chromosome 22.
Dilutions
WB 1:500 - 1:2000
IHC 1:50 - 1:100
IF 1:50 - 1:100
Format
Calculated MW
36kDa/75kDa/76kDa/79kDa
Observed MW
Refer to Figures
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-324 of human HPS1 (NP_872577.1).
Modification
Unmodified
Storage
-20°C
Images
Immunohistochemistry of paraffin-embedded mouse stomach using HPS1 antibody (144-06621) at dilution of 1:100 (40x lens).

Immunohistochemistry of paraffin-embedded rat kidney using HPS1 antibody (144-06621) at dilution of 1:100 (40x lens).

Immunohistochemistry of paraffin-embedded human stomach using HPS1 antibody (144-06621) at dilution of 1:100 (40x lens).

Immunofluorescence analysis of MCF7 cells using HPS1 antibody (144-06621). Blue: DAPI for nuclear staining.

Expiration:
12 months from the date of shipment when stored properly.