Background
The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.
Dilutions
WB 1:500 - 1:2000
IF 1:50 - 1:200
Format
Calculated MW
39kDa/40kDa/42kDa/45kDa
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 220-345 of human PVR (NP_006496.4).
Modification
Unmodified
Storage
-20°C
Images
Western blot analysis of extracts of LO2 cells, using PVR antibody (144-05753) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 90s.

Expiration:
12 months from the date of shipment when stored properly.