Introduction
Phosphorylates 'Ser-789' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators.
Other Information
NCBI Accession #
NP_848825.2
Antigen Type
Synthetic Peptide
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Calculated Molecular Weight (Da)
104198
Images
WB (1:1000)
Mouse Sik2 Antibody (Center) (Cat. #102-22749) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the Sik2 antibody detected the Sik2 protein (arrow).

Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.