Introduction
ELF4 is transcriptional activator that binds to DNA sequences containing the consensus 5'-WGGA-3'. The protein acts synergistically with RUNX1 to transactivate the IL3 promoter. Also transactivates the PRF1 promoter in natural killer (NK) cells. This protein plays a role in the development and function of NK and NK T-cells and in innate immunity.
Specificity
Predicted Reactivity
Mouse, Bovine
Other Names
ELF4; ELFR; MEF; ETS-related transcription factor Elf-4; E74-like factor 4; Myeloid Elf-1-like factor
NCBI Accession #
NP_001120669.1;NP_001412.1
Other Accession #
Q9Z2U4; Q60775; P32519; A0JN51
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
70730
Recommended Dilutions
WB: 1:1000; FC: 1:10-50
 | ELF4 Antibody (Center) (Cat# 102-17167) western blot analysis in HL-60,K562 cell line lysates (35ug/lane).This demonstrates the ELF4 antibody detected the ELF4 protein (arrow). |
 | Flow cytometric analysis of NCI-H292 cells using ELF4 Antibody (Center)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.