Introduction
Members of the 'with no lysine' (WNK) kinase family, such as WNK3, are serine-threonine protein kinases that lack the almost invariant catalytic lysine in subdomain II, which is important for binding ATP in the catalytic site. Instead, these kinases have a conserved lysine in subdomain I that is thought to provide this function (Holden et al., 2004 [PubMed 15194194]).[supplied by OMIM]
Specificity
Other Names
Protein kinase WNK3
NCBI Accession #
NP_001002838.1;NP_065973.2
Other Accession #
Q9BYP7-2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
198416
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | PRKWNK3 Antibody (Cat# 102-17102) western blot analysis in uterus tumor cell line lysates (35ug/lane).This demonstrates the PRKWNK3 antibody detected the PRKWNK3 protein (arrow). |
 | WNK3(PRKWNK3) Antibody (C-term) (Cat# 102-17102)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of WNK3(PRKWNK3) Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.