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Anti-THOC6 (Center) Antibody
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Rabbit Anti-THOC6 (Center) Antibody, 400 ul
原料试剂 动物实验室研发实验室
价格
3841
品牌 瑞博奥/RayBio
地区 -
货号 102-13928
产地 进口
选择规格
400 µl
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RayBio多因子检测
瑞博奥(广州)生物科技股份有限公司
中国广东省广州市
营业执照已审核
RayBio是一家总部位于美国乔治亚州的生物技术公司,专注于开发和制造高质量的蛋白质检测工具以及提供相应的服务,聚焦于蛋白质组学的检测分析领域和多组学的应用,以严格的质量控制和创新的技术为基础。 Raybio具有可用于生命科学研究、疾病研究及疾病治疗相关药物、医学技术等功能探究的全线产品,包括国际领先、最多专利、最多指标的抗体芯片、流式多因子芯片等多因子检测试剂盒超700余种;单靶标检的ELISA试剂盒,可用于细胞因子含量、药物作用等检测;以及超过18,000种抗体、小分子产品,可用于WB、ELISA、IF等免疫学实验。 我们的产品和服务被全球的学术、政府和制药实验室广泛使用,用于疾病诊断、药物筛选和基础研究,已助力全球客户在Nature, Nature Medicine, Cell, Lancet, PNAS等世界顶级期刊上发表了数万篇文章。
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产品规格 图文详情 技术文档
产品规格
品牌名称
瑞博奥/RayBio
货号
102-13928
国产/进口
进口
规格
400 µl
图文详情

Introduction

Component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing-and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between THOC4 and the cap-binding protein NCBP1. UAP56 functions as a bridge between THOC4 and the THO complex. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. The recruitment of the TREX complex to the intronless viral mRNA occurs via an interaction between KSHV ORF57 protein and THOC4.

Specificity

Predicted Reactivity
Rat
Other Names
THOC6; WDR58; THO complex subunit 6 homolog; Functional spliceosome-associated protein 35; WD repeat-containing protein 58
NCBI Accession #
NP_001135822.1;NP_077315.2
Other Accession #
Q6AY87; Q5U4D9; NP_001135822.1

Format

Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
37535
Recommended Dilutions
WB: 1:1000
THOC6 Antibody (Center) (Cat# 102-13928) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the THOC6 antibody detected the THOC6 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.
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