Introduction
This locus encodes a GTP-binding protein. The encoded protein is localized to the mitochondria and may play a role in mitochondrial tRNA modification. Polymorphisms at this locus may be associated with severity of aminoglycoside-induced deafness, a disease associated with a mutation in the 12S rRNA. Alternatively spliced transcript variants encoding different isoforms have been described.
Specificity
Other Names
GTPBP3; MTGP1; tRNA modification GTPase GTPBP3, mitochondrial; GTP-binding protein 3; Mitochondrial GTP-binding protein 1
NCBI Accession #
NP_001122327.1;NP_001182351.1;NP_116009.2;NP_598399.2
Other Accession #
NP_116009.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
52058
Recommended Dilutions
WB: 1:1000
 | GTPBP3 Antibody (Center) (Cat# 102-14314) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the GTPBP3 antibody detected the GTPBP3 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.