Introduction
NR5A2 binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May be responsible for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.
Specificity
Other Names
NR5A2; B1F; CPF; FTF; Nuclear receptor subfamily 5 group A member 2; Alpha-1-fetoprotein transcription factor; B1-binding factor; CYP7A promoter-binding factor; Hepatocytic transcription factor; Liver receptor homolog 1
NCBI Accession #
NP_001263393.1;NP_003813.1;NP_995582.1
Other Accession #
NP_003813.1; NP_995582.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
61331
Recommended Dilutions
WB: 1:1000
 | NR5A2 Antibody (Center) (Cat# 102-13228) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the NR5A2 antibody detected the NR5A2 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.