已关闭
收藏细胞基因敲除效率:100%
LRMP NCBI Gene ID:4033
LRMP Ensembl ID:ENSG00000118308
LRMP Uniprot ID: Q12912
LRMP基因介绍:Plays a role in the delivery of peptides to major histocompatibility complex (MHC) class I molecules; this occurs in a transporter associated with antigen processing (TAP)-independent manner. May play a role in taste signal transduction via ITPR3. May play a role during fertilization in pronucleus congression and fusion. Plays a role in maintaining nuclear shape, maybe as a component of the LINC complex and through interaction with microtubules.
细胞生长培养基:专用培养基
细胞培养条件:37℃,5% CO2 的培养箱,1/2 到 1/3 传代
细胞倍增时间:~60 hours
细胞支原体检测结果:阴性
细胞开发路径:采用CRISPR-RNP方法生成稳定KO Cell line;Sanger 测序结果显示KO Cell line敲除效率100%。
细胞应用:高敲除效率的基因敲除细胞系(KO Cell line),特别适用于初步功能分析、复杂疾病模型的开发、精准药物筛选以及广泛的基因发现研究。