细胞基因敲除效率：100%

ALDH1A2 NCBI Gene ID：116676

ALDH1A2 Ensembl ID：ENSRNOG00000055049

ALDH1A2 Uniprot ID： Q63639

ALDH1A2基因介绍：Catalyzes the NAD-dependent oxidation of aldehyde substrates, such as all-trans-retinal and all-trans-13,14-dihydroretinal, to their corresponding carboxylic acids, all-trans-retinoate and all-trans-13,14-dihydroretinoate, respectively (By similarity) (PubMed:8663198). Retinoate signaling is critical for the transcriptional control of many genes, for instance it is crucial for initiation of meiosis in both male and female (By similarity). Recognizes retinal as substrate, both in its free form and when bound to cellular retinol-binding protein (PubMed:8663198). Lacks activity with benzaldehyde, acetaldehyde and octanal (PubMed:8663198). Displays complete lack of activity with citral (PubMed:8663198)

细胞生长培养基：专用培养基

细胞培养条件：37℃,5% CO2 的培养箱，1/2 到 1/4 传代

细胞倍增时间：~24-36 hours

细胞支原体检测结果：阴性

细胞开发路径：采用CRISPR-RNP方法生成稳定KO Cell line；Sanger 测序结果显示KO Cell line敲除效率100%。

细胞应用：高敲除效率的基因敲除细胞系（KO Cell line），特别适用于初步功能分析、复杂疾病模型的开发、精准药物筛选以及广泛的基因发现研究。