细胞基因敲除效率：100%

NRIP1 NCBI Gene ID：8204

NRIP1 Ensembl ID：ENSG00000180530

NRIP1 Uniprot ID： P48552

NRIP1基因介绍：Modulates transcriptional activation by steroid receptors such as NR3C1, NR3C2 and ESR1. Also modulates transcriptional repression by nuclear hormone receptors. Positive regulator of the circadian clock gene expression: stimulates transcription of ARNTL/BMAL1, CLOCK and CRY1 by acting as a coactivator for RORA and RORC. Involved in the regulation of ovarian function (By similarity). Plays a role in renal development (PubMed:28381549).

细胞生长培养基：RPMI-1640+10%FBS+1%P/S

细胞培养条件：37℃,5% CO2 的培养箱，1/2 到 1/4传代

细胞倍增时间：~24-36 hours

细胞支原体检测结果：阴性

细胞开发路径：采用CRISPR-RNP方法生成稳定KO Cell line；Sanger 测序结果显示KO Cell line敲除效率100%。

细胞应用：高敲除效率的基因敲除细胞系（KO Cell line），特别适用于初步功能分析、复杂疾病模型的开发、精准药物筛选以及广泛的基因发现研究。