Application:IF
Reactivity: Rat (predicted: Human,Mouse,Rabbit,Pig,Sheep,Cow,Dog,Horse)
RSPO1 is a member of the R-spondin family and encodes a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects.