图文详情
Application:IF,Flow-Cyt,ICC/IF
Reactivity: Human (predicted: Mouse,Rat,Rabbit,Pig,Cow)
Cullin 1 may be involved in the degradation of positive cell cycle regulators (for example G1 cyclins in yeast). Human cullin 1 forms a complex with Skp1 and the F box protein Skp2, which is thought to play a role in the ubiquitination of G1 regulatory proteins, as its homolog does in yeast.