图文详情
Application:Flow-Cyt
Reactivity: Mouse (predicted: Human,Rat,Pig,Cow,Chicken,Dog,Horse)
This gene encodes a HECT domain and ankyrin repeat-containing ubiquitin ligase. The encoded protein is involved in specific tagging of target proteins, leading to their subcellular localization or proteasomal degradation. The protein is a potential tumor suppressor and is involved in the pathophysiology of several tumors, including Wilm's tumor. [provided by RefSeq, Mar 2016]