图文详情
Application:WB
Reactivity: Human (predicted: Mouse,Rat,Rabbit,Pig,Cow,Dog,Horse)
The protein encoded by this gene catalyzes the conversion of sulfated steroid precursors to estrogens during pregnancy. The encoded protein is found in the endoplasmic reticulum, where it acts as a homodimer. Mutations in this gene are known to cause X-linked ichthyosis (XLI). [provided by RefSeq, Jul 2008].