Application:IF
Reactivity: (predicted: Human,Mouse,Rat)
Kallikreins (KLKs) are a subgroup of trypsin-like serine proteases and are implicated in carcinogenesis. Kallikrein 2 is most closely related to Kallikrein 3 (PSA), with 78% identity and with kallikrein 1, at 68% identity. Like Kallikrein 3, Kallikrein 2 is found in greatest abundance in the prostate, but at much lower levels than Kallikrein 3. In addition, Kallikrein 2 seems to be more labile than Kallikrein 1 or Kallikrein 3 and is often found in a cleaved form. Kallikrein 2 is inhibited by Protein C Inhibitor (PCI).