图文详情
Application:IF
Reactivity: (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Dog)
Exonuclease with activity against single- and double-stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis.