图文详情
Application:IF
Reactivity: Rat (predicted: Human,Mouse,Rabbit,Pig,Sheep,Cow,Dog,Horse)
SMC5/6 complex is recruited to nuclease induced double strand breaks (DSBs) and is required for the recruitment of cohesin to DSBs. The human SMC5/6 complex and the SUMO ligase activity of hMMS21 are required for the prevention of DNA damage induced apoptosis by facilitating DNA repair in human cells.