图文详情
Application:IF
Reactivity: Mouse,Rat (predicted: Human,Rabbit,Pig,Cow,Horse)
Crkl is a 34kDa adaptor protein which has been shown to activate the RAS and JUN kinase signalling pathways and transforms fibroblasts in a RAS dependant manner. Crkl is a substitute of BCR ABL tyrosine kinase. In addition, Crkl has oncogenic potential.