Application:WB
Reactivity: Human,Rat (predicted: Mouse,Rabbit,Sheep,Cow,Chicken,Dog,Horse)
FRMD4A is a 1,039 amino acid protein that localizes to cytoplasm and contains one FERM domain. The gene encoding FRMD4A maps to human chromosome 10p13. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4.5% of total DNA in cells and encodes nearly 1,200 genes. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria