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TBP Rabbit pAb, BF405 conjugated
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原料试剂 研发实验室
价格
￥2980.00
品牌 Bioss博奥森生物
地区 中国,北京,北京市
货号 bs-11766R-BF405
产地 国产
选择规格
100ul
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Bioss博奥森生物
北京博奥森生物技术有限公司
北京
博奥森：专注科研，以优质抗体引领未来
博奥森生物，自2001年诞生以来，始终坚守在生命科学前沿，为全球科研人员提供卓越品质的免疫学试剂产品与服务。我们拥有资深的科学家团队、先进的抗体发现、验证与生产平台，始终坚持“自主研发、原始创新”的理念，确保每一款产品都能达到国际标准，持续提供“4R” 品质科研工具【Repeatable（可重复）、Replicable（可复制）、Reproducible（可再现）和Reliable（可靠的）】。
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产品规格
图文详情
技术文档
产品规格
品牌名称
Bioss博奥森生物
货号
bs-11766R-BF405
国产/进口
国产
规格
100ul
储存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
使用范围
IF
货源
新品
图文详情
Application:IF
Reactivity: Human,Mouse (predicted: Rat,Rabbit,Pig,Cow,Chicken,Dog,Horse)
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. The number of CAG repeats encoding the polyglutamine tract is usually 25-42, and expansion of the number of repeats to 45-66 increases the length of the polyglutamine string and is associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2016]
Reactivity: Human,Mouse (predicted: Rat,Rabbit,Pig,Cow,Chicken,Dog,Horse)
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. The number of CAG repeats encoding the polyglutamine tract is usually 25-42, and expansion of the number of repeats to 45-66 increases the length of the polyglutamine string and is associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2016]
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