图文详情
Application:IHC-P,IHC-F
Reactivity: Human,Mouse,Rat (predicted: Rabbit,Pig,Cow,Horse)
Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity.