图文详情
Application:WB,IHC-P,IHC-F,IF,Flow-Cyt
Reactivity: Human,Mouse (predicted: Rat,Rabbit,Pig,Cow,Dog)
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011].