图文详情
Application:IF,Flow-Cyt
Reactivity: Human (predicted: Mouse,Rat,Rabbit,Pig,Cow,Chicken,Dog,Horse)
Transcriptional factor that uses the canonical single or multiple CArG boxes DNA sequence. Binds CArG boxes only in the presence of serum response factor (SRF). Acts as a cofactor of SRF and modulates SRF-target genes. Regulates the expression of a set of cardiac and smooth muscle-specific genes. Plays a crucial role in cardiogenesis and differentiation of the smooth muscle cell lineage.