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human CD19 Mouse mAb, APC-Cy5.5 conjugated
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原料试剂 研发实验室
价格
￥3880.00
品牌 Bioss博奥森生物
地区 中国,北京,北京市
货号 bsm-30096M-APC-Cy5.5
产地 国产
选择规格
100T
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Bioss博奥森生物
北京博奥森生物技术有限公司
北京
博奥森：专注科研，以优质抗体引领未来
博奥森生物，自2001年诞生以来，始终坚守在生命科学前沿，为全球科研人员提供卓越品质的免疫学试剂产品与服务。我们拥有资深的科学家团队、先进的抗体发现、验证与生产平台，始终坚持“自主研发、原始创新”的理念，确保每一款产品都能达到国际标准，持续提供“4R” 品质科研工具【Repeatable（可重复）、Replicable（可复制）、Reproducible（可再现）和Reliable（可靠的）】。
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产品规格
图文详情
技术文档
产品规格
品牌名称
Bioss博奥森生物
货号
bsm-30096M-APC-Cy5.5
国产/进口
国产
规格
100T
储存条件
Store at 2-8℃. Protect from light. Avoid freezing.
使用范围
Flow-Cyt
货源
新品
图文详情
Application:Flow-Cyt
Reactivity: Human
This gene encodes a member of the immunoglobulin gene superfamily. Expression of this cell surface protein is restricted to B cell lymphocytes. This protein is a reliable marker for pre-B cells but its expression diminishes during terminal B cell differentiation in antibody secreting plasma cells. The protein has two N-terminal extracellular Ig-like domains separated by a non-Ig-like domain, a hydrophobic transmembrane domain, and a large C-terminal cytoplasmic domain. This protein forms a complex with several membrane proteins including complement receptor type 2 (CD21) and tetraspanin (CD81) and this complex reduces the threshold for antigen-initiated B cell activation. Activation of this B-cell antigen receptor complex activates the phosphatidylinositol 3-kinase signalling pathway and the subsequent release of intracellular stores of calcium ions. This protein is a target of chimeric antigen receptor (CAR) T-cells used in the treatment of lymphoblastic leukemia. Mutations in this gene are associated with the disease common variable immunodeficiency 3 (CVID3) which results in a failure of B-cell differentiation and impaired secretion of immunoglobulins. CVID3 is characterized by hypogammaglobulinemia, an inability to mount an antibody response to antigen, and recurrent bacterial infections. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2020]
Reactivity: Human
This gene encodes a member of the immunoglobulin gene superfamily. Expression of this cell surface protein is restricted to B cell lymphocytes. This protein is a reliable marker for pre-B cells but its expression diminishes during terminal B cell differentiation in antibody secreting plasma cells. The protein has two N-terminal extracellular Ig-like domains separated by a non-Ig-like domain, a hydrophobic transmembrane domain, and a large C-terminal cytoplasmic domain. This protein forms a complex with several membrane proteins including complement receptor type 2 (CD21) and tetraspanin (CD81) and this complex reduces the threshold for antigen-initiated B cell activation. Activation of this B-cell antigen receptor complex activates the phosphatidylinositol 3-kinase signalling pathway and the subsequent release of intracellular stores of calcium ions. This protein is a target of chimeric antigen receptor (CAR) T-cells used in the treatment of lymphoblastic leukemia. Mutations in this gene are associated with the disease common variable immunodeficiency 3 (CVID3) which results in a failure of B-cell differentiation and impaired secretion of immunoglobulins. CVID3 is characterized by hypogammaglobulinemia, an inability to mount an antibody response to antigen, and recurrent bacterial infections. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2020]
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