图文详情
Application:WB,IHC-P,IHC-F,IF
Reactivity: Mouse (predicted: Human,Rat,Rabbit,Pig,Sheep,Cow,Dog)
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. [provided by RefSeq, Jul 2008]