图文详情
Application:WB
Reactivity: Mouse (predicted: Rat)
MRGPRA, Mas-related G-protein coupled receptor member A, is an orphan receptor activated by a subset of RFamide-family neuropeptides such as FLRF-amide and FMRF-amide. It mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins and it may regulate the function of nociceptive neurons by modulation of pain perception.