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FA20A belongs to the FAM20 family. All FAM20 proteins contain putative conserved signal sequences as well as a conserved C terminal domain. FA20A is a secreted glycoprotein. It has been found in EML and MPRO cell lines, with low levels in undifferentiated cells. FA20A is induced during maturation to promyelocyte stage of neutrophil differentiation and decreased during neutrophil terminal differentiation.