Stored at -70°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -70°C for extended storage. Avoid repeated freeze/thaw cycles.
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RSPO1 activates the canonical Wnt signaling pathway by binding to the LGR4-6 receptor, triggering an increase in target gene expression. It inhibits ZNRF3, regulates the Wnt signaling pathway, and negatively regulates the TGF-β pathway.